Grafts in Path of Exile are among the most impactful new systems introduced during the Keepers of the Flame League. While they're often associated with breaking Hive Walls and collecting Graftblood, their true value lies in their unique offensive and defensive bonuses. Each Graft provides an implicit stat boost and a powerful active skill that can seriously improve your survivability, clear speed, or endgame DPS.

As you progress through the League's story and upgrade the Genesis Tree, you'll eventually unlock the ability to equip two Grafts at the same time. This opens the door to synergistic builds that can completely transform your gameplay. However, with 16 total Grafts available, finding the strongest combo can be overwhelming.

To help you pick the best setups, here are five top-tier Graft combos in Path of Exile, hand-selected for performance, synergy, and versatility across mapping and bossing.

1) Molten Xophgraft + Impaling Uulgraft

Best for: Melee builds, tanky characters, Duelist & Marauder archetypes

If you want a combo that excels at both offense and defense, Molten Xophgraft paired with Impaling Uulgraft is an excellent choice. Molten Xophgraft increases your armor by up to 20% and grants Heart of Flame, a skill that gives you a damage-absorbing shield whenever you're missing life. In addition, it fires explosive projectiles that hit extremely hard-perfect for melee players who take consistent damage.

Impaling Uulgraft complements this perfectly. It's implicit increases your chance to Impale enemies by up to 12%. Since Impale reflects a portion of the enemies' damage taken back at them, this scales the DPS of many physical builds. Its granted skill, Violent Desire, gives a 30% chance to inflict another Impale and increases Impale effect by up to 26%.

Why it works:

·Both are excellent for characters that fight in close range.

·You get strong mitigation from Molten Xophgraft and amplified physical scaling from Impaling Uulgraft.

·One of the best combos for melee Gladiator, Slayer, or Juggernaut-style builds.

For players who want to enhance their melee scaling even further, investing in certain Path of Exile Items like Impale jewels or physical-to-elemental conversion gear can take this combo to another level.

2) Battering Uulgraft + Replicating Eshgraft

Best for: Single-target DPS, bossing, map elites

This is one of the most popular combos for players pushing into high-tier content or fighting bosses like Hive Fortress enemies. Battering Uulgraft grants Return to Dust, a powerful skill that slams the ground with giant ethereal hands every 10 seconds. This deals massive damage, stuns enemies, and can even interrupt attacks.

Pair this with Replicating Eshgraft, and you gain lightning clones that actively seek out tankier enemies and explode for high burst damage. These clones leave behind Shock Ground, causing enemies to take 15% increased damage-perfect for improving single-target DPS.

Why it works:

·One of the strongest bossing combos available.

·Return to Dust offers AoE and control, while lightning clones add consistent, targeted damage.

·Amazing for any build lacking single-target power.

If you're investing in endgame bossing, you can also buy POE Currency to craft better gear that synergizes with these Grafts, especially items that scale physical or lightning damage.

3) Erupting Xophgraft + Draining Eshgraft

Best for: AoE clear, hybrid damage scaling, explosive gameplay

If you enjoy screen-wide destruction, this combo is perfect. Erupting Xophgraft provides increased AoE damage and the skill His Burning Message, which creates fiery geysers that spam flaming projectiles. When you manually use a Warcry, these geysers double their attack rate-turning them into boss-melting turrets.

Combine this with Draining Eshgraft, which increases the AoE of your spells and grants Enervating Grasp, a skill that places lightning "landmines" that detonate for AoE damage and apply Sap, reducing enemy damage output.

Why it works:

·Massive AoE coverage from both fire and lightning abilities.

·Great for clearing maps quickly and deleting bosses at mid-tier content.

·Extremely fun to play-perfect for players who enjoy flashy builds.

4) Summoning Tulgraft + Storming Eshgraft

Best for: Minion builds, hybrid summoner-caster setups, Chayula players

If you're running a minion build in Path of Exile, Summoning Tulgraft is almost mandatory. It grants The Great Avalanche, letting you summon up to 30 Hiveborn minions if you build correctly. These minions have solid attack and cast speed, letting them overwhelm enemies quickly.

To increase your personal damage while focusing on minions, pair it with Storming Eshgraft. This adds lightning damage to your attacks and grants Wreathed in Light, which rains lightning bolts and creates Radiant Ground-granting your allies Lucky damage rolls.

Why it works:

·Perfect synergy for high-pressure minion playstyles.

·Great for mapping, Hive encounters, and even bossing

5) Jolting Eshgraft + Stoking Xophgraft

Best for: Crit builds, high-risk, high-reward damage, ailment-based scaling

Lastly, Jolting Eshgraft is a go-to for crit builds. It grants up to 30% more attack damage through Jolt stacks (up to 10), and increases global crit chance by up to 12%. However, Jolt also increases the damage you take-making this a risky but rewarding setup.

Pairing it with Stoking Xophgraft removes this downside. Stoking periodically removes all ailments from you and converts 33% of your physical damage into an elemental type based on the ailment removed. This lets you convert Jolt into massive bonus elemental damage, while cleansing the defensive drawback.

Why it works:

·Turns a dangerous Graft into a safe and powerful one.

·Provides consistent elemental conversion for more scaling.

·Excellent for fast-hitting crit builds like Ranger, Assassin, or Duelist.

Final Thoughts

Grafts are one of the most creative and versatile systems introduced in Path of Exile's Keepers of the Flame League. Whether you prefer massive AoE explosions, high-damage melee strikes, or overwhelming minion armies, there's a combo tailored to your playstyle. As the Genesis Tree expands, players will continue discovering new synergies-but these five combinations represent some of the strongest and most reliable setups right now.